TA vs MGO

Comparison of TA and MGO Honey

Functional honey is known for its strong antimicrobial properties, and two of the most prominent types are TA (Total Activity) and MGO (Methylglyoxal) honey.

TA Honey

TA honey, such as West Australian Jarrah and Marri, is characterized by its high hydrogen peroxide (H2O2) activity. This activity occurs when the honey is diluted and H2O2 is produced through the enzyme glucose oxidase, which the bees add during honey maturation. TA honey is measured by Total Activity (TA), which tests the honey’s ability to inhibit bacterial growth. A TA of 10+ is considered functional quality and is effective in treating topical infections.

MGO Honey

MGO honey, like the famous Australian Manuka, contains methylglyoxal, a plant-derived compound with strong antimicrobial properties. Unlike TA honey, MGO deactivates glucose oxidase, meaning that MGO honey does not contain H2O2. The level of MGO in the honey indicates its potency, with higher MGO concentrations (e.g. 1,000 mg/kg) indicating a stronger antimicrobial effect.

Comparison

• Antimicrobial Effect : Both TA and MGO honey are effective against bacteria, but they work in different ways. TA honey is based on H2O2 production, while MGO honey uses methylglyoxal.
• Measurement : TA is measured by Total Activity, which is calibrated against a phenol solution, while MGO honey is measured directly by the concentration of methylglyoxal.
• Uses : Both types of honey are suitable for wound care and treating infections. The choice between TA and MGO honey depends on the specific application and the desired strength.